Patient handout

IgE-mediated food allergy

PRODUCTION

1. Your condition

This handout is for ige-mediated food allergy. Your care team identified this based on: reproducible food-triggered urticaria/angioedema/wheeze/gi/anaphylaxis within minutes-2h of ingestion (eaaci 2025 pmid 39473345).

Other reasons your team may use this plan: positive food-specific ige or skin-prick test in the setting of a compatible history (eaaci 2025 pmid 39473345); prior food-triggered anaphylaxis requiring epinephrine — referred from allergy.anaphylaxis.v1 for chronic disease management; high-risk infant (severe eczema and/or egg allergy) 4-11 mo — leap-based early peanut introduction window (pmid 25705822).

2. Your medications

Take these medications exactly as prescribed. Do not stop or change a dose without talking to your provider.

Medication	Starting dose	How	When	What it does
strict_allergen_avoidance_and_label_reading	—	—	—	EAACI 2025 (PMID 39473345) — confirmed IgE-FA mandates strict avoidance with dietitian-supported nutritional adequacy and label-reading education.
written_emergency_action_plan	—	—	—	EAACI 2025 (PMID 39473345) — every patient receives a written action plan documenting trigger, recognition, when to use epinephrine, and when to call emergency services.
epinephrine	0.15 mg IM (7.5-25 kg) / 0.3 mg IM (>=25 kg)	IM lateral thigh	PRN for systemic reaction; may repeat in 5-15 min	EAACI 2025 (PMID 39473345) — IM epinephrine is the first-line rescue for anaphylaxis; at-risk patients carry two auto-injectors. Technique re-taught at every visit.

Plan: IgE-mediated food allergy — avoidance + emergency action plan + immunomodulatory disease-modifying therapy (EAACI 2025)

3. When to call your provider

Contact your care team if any of the following happen:

Systemic reaction in progress (two-organ system / cardiovascular / airway) → route to allergy.anaphylaxis.v1 for IM epinephrine + supportive care
New dysphagia / food impaction during OIT → endoscopy for EoE (OIT class effect)
Baseline tryptase >=11.4 ng/mL or recurrent unexplained anaphylaxis → mast-cell disorder workup (route allergy.mast-cell-activation-syndrome.core.v1)

4. When to seek emergency care

Call 911 or go to the nearest emergency room right away if you have:

Active reaction with two-organ system involvement OR cardiovascular compromise OR airway compromise(life-threatening)

5. Follow-up

Lifelong chronic-allergy maintenance: written action plan + auto-injector + label-reading habit + school/workplace plan + medical-alert identification. School staff training in epinephrine administration. Re-evaluation for natural tolerance (milk/egg/wheat childhood allergies) via supervised OFC at allergist discretion. Lifelong avoidance counselling for peanut/tree-nut/sesame/shellfish (low natural-tolerance rate).

6. Sources

Guideline: EAACI 2025 IgE-mediated food allergy guideline (Santos et al, Allergy 2024-10; PMID 39473345); LEAP NEJM 2015 (Du Toit; PMID 25705822); PALISADE NEJM 2018 (PMID 30449234); OUtMATCH NEJM 2024 (Wood; PMID 38407394); EPITOPE phase 3 extension 2025 (PMID 40204253; PMID 39956162)