This handout is for aortic stenosis (calcific + bicuspid + rheumatic; high-gradient & low-flow/low-gradient). Your care team identified this based on: classic as triad — exertional syncope, angina, or hf (2020 acc/aha vhd §3.2).
Other reasons your team may use this plan: progressive dyspnea on exertion in known as (2020 acc/aha vhd §3.2); late-peaking systolic ejection murmur with diminished/absent a2 (etchells jama 1997 pmid 9032164); incidental severe as on screening echo (2020 acc/aha vhd §3.2.3).
Take these medications exactly as prescribed. Do not stop or change a dose without talking to your provider.
| Medication | Starting dose | How | When | What it does |
|---|---|---|---|---|
| clinical surveillance (no AS-directed pharmacotherapy) | — | — | — | No drug slows AS: SEAS AVR HR 1.00 (0.84–1.18) PMID 18765433; ASTRONOMER annualised peak-gradient rise 6.3 vs 6.1 mmHg/y P=0.83 PMID 20048204; SALTIRE no effect PMID 15944423. Surveillance TTE q1–2 y (moderate) per 2020 ACC/AHA VHD §3.2.5 |
| atorvastatin | 40–80 mg | PO | once daily | For independent ASCVD risk ONLY — does NOT slow AS (SEAS ischaemic-event HR 0.78 (0.63–0.97) reflects ASCVD benefit, AS-event HR 1.00; PMID 18765433) |
Plan: AS severity/symptom-staged management ladder (2020 ACC/AHA VHD §3.2; EARLY-TAVR/RECOVERY/AVATAR era)
Contact your care team if any of the following happen:
Call 911 or go to the nearest emergency room right away if you have:
Cardiology / valve clinic; endocarditis prophylaxis after prosthetic AVR; lifestyle; vaccinations (2020 ACC/AHA VHD §3.2.5)
Guideline: 2020 ACC/AHA Valvular Heart Disease Guideline (current 2026; full ACC/AHA revision planned late 2026) + 2021 ESC/EACTS VHD; EARLY-TAVR-era evidence layered on