Atypical / scar-mediated / left atrial flutter
Phase E variant of cardio.atrial_flutter.v1 — narrowed to atypical / scar-mediated / left atrial macroreentrant flutter (NOT using cavotricuspid isthmus). Substrate includes post-PVI, post-CABG, post-MAZE, post-valve, post-transplant, congenital HD, or RA non-CTI scar. Inherits AC + acute rate/rhythm management from parent; specializes the 3D electroanatomic mapping ablation pathway, scar-substrate AAD selection (amiodarone first-line; flecainide CONTRAINDICATED per CAST), mixed AF/AFL management, and post-LA-ablation atrioesophageal fistula surveillance. Ablation success rate 60–80% (lower than CTI) per Aliot 2009 (PMID 19324313); 3D electroanatomic mapping required to identify circuit. Mixed AF/AFL coexistence is the RULE rather than exception — lifelong AC typical even after successful ablation. Post-LA-ablation atrioesophageal fistula incidence ~0.1–0.25% with ~80% mortality — HIGHER RISK than CTI ablation; warning signs (fever + chest pain + neuro deficit weeks 2–6) require emergency surgical evaluation. Amiodarone first-line AAD given structural HD substrate; flecainide/propafenone CONTRAINDICATED per CAST (PMID 1900101). Manifest pointer reuses cardio.atrial_flutter.v1 manifest. Design-brief pointer reuses parent. Status INTEGRATED until terminology + RxNav-validated drug codes are reconciled. Authored 2026-05-14 by shard-06-cardio-acute.
Entry points (3)
- imagingFlutter waves NOT meeting typical CTI criteria — positive in II/III/aVF, prominent V1, variable axisatypical_flutter_morphology_on_ecg
- historyRecurrent atrial flutter after prior AF ablation (PVI), MAZE, CABG, valve, or transplant — scar-mediated reentryrecurrent_aflutter_post_pvi_or_cardiac_surgery
- symptomPalpitations / dyspnea / fatigue in patient with prior left atrial intervention or congenital heart diseasepalpitations_in_post_cardiac_surgery_patient
Required inputs (11)
- agerequireddemographic • used at CONTEXTCHA2DS2-VASc + ablation candidacy
- sbprequiredvital • used at RED_FLAGSSBP <90 with flutter RVR → emergent DCCV 100–200 J biphasic (atypical may need higher energy than typical)
- hrrequiredvital • used at CONTEXTConduction ratio variable (1:1, 2:1, 3:1) — atypical flutter has more variable AV ratios
- ecg_12_leadrequiredimaging • used at INITIAL_WORKUPAtypical morphology — positive flutter waves II/III/aVF, prominent V1 (mitral isthmus, roof-dependent, or LA-scar circuit) — Saoudi 2001 (PMID 11428013); Aliot 2009 (PMID 19324313)
- prior_pvi_maze_cabg_valve_transplantrequiredhistory • used at CONTEXTIdentifies scar substrate; ~30–50% of post-PVI patients develop atypical LA flutter (Patel 2008 PMID 18272844)
- creatinine_egfrrequiredlab • used at INITIAL_WORKUPDOAC + AAD dosing; contrast for 3D mapping/ablation
- tshrequiredlab • used at INITIAL_WORKUPReversible cause screen; amiodarone-induced thyroid dysfunction common in this population
- tterequiredimaging • used at INITIAL_WORKUPLA size, EF, valvular function, prior surgical anatomy review; LA appendage thrombus screen pre-ablation
- tee_or_cardiac_ct_pre_ablationimaging • used at TREATMENTLA appendage thrombus exclusion + chamber anatomy for 3D mapping — required pre-LA ablation
- cha2ds2_vasc_factorsrequiredhistory • used at RISK_STRATIFICATIONAC indication identical to AF
- bleeding_historyrequiredhistory • used at RISK_STRATIFICATIONHAS-BLED + ablation peri-procedure bleed risk
12-phase flow (11)
- 1FRAMEConfirm atypical (NON-CTI) flutter — morphology not meeting typical sawtooth criteria + history of LA scar substrate (post-PVI, post-CABG, post-MAZE, post-valve, congenital HD); often coexists with AFinputs: ecg_12_lead, prior_pvi_maze_cabg_valve_transplantadvance: Atypical morphology + scar substrate confirmed
- 2ENTRYPalpitations / dyspnea / fatigue / syncope / incidental telemetry, often in post-cardiac-surgery or post-PVI patientinputs: ageadvance: Engine entered
- 3CONTEXTPrior PVI / MAZE / CABG / valve / transplant / congenital surgical repair; structural HD; prior AAD trials (often refractory); current meds + AVN-blocker reviewinputs: hr, cha2ds2_vasc_factors, bleeding_history, prior_pvi_maze_cabg_valve_transplantadvance: Context complete
- 4RED_FLAGSHemodynamic instability (SBP <90, pulmonary edema, ischemia, AMS) → synchronized DCCV 100–200 J biphasic now (atypical often needs higher energy than typical)inputs: sbpactions: tachycardiaadvance: Stable or cardioverted
- 5INITIAL_WORKUPECG, TSH, BMP/Mg, creatinine, CBC, BNP, TTE — baseline + structural anatomy reviewinputs: ecg_12_lead, tsh, creatinine_egfr, tteactions: panel.cardiac, panel.thyroid, panel.renaladvance: Stage-1 returned
- 6BRANCHING_WORKUPTEE or cardiac CT to exclude LA appendage thrombus before any planned ablation; concomitant AF surveillance (Holter — high overlap); chest-pain comorbid → acs_pathwayinputs: tee_or_cardiac_ct_pre_ablationactions: acs_pathway, afib_new_onsetadvance: Branch resolved
- 7RISK_STRATIFICATIONCHA2DS2-VASc (AC indication identical to AF) + HAS-BLED + eGFR for DOAC + AAD doseinputs: cha2ds2_vasc_factors, bleeding_historyadvance: Risk tier documented
- 8TREATMENTAcute: rate control (BB or non-DHP CCB) + amiodarone often required given structural HD; ibutilide less effective for atypical (lower conversion rate); often need DCCV. Long-term: 3D electroanatomic mapping + ablation (success 60–80%, lower than CTI); AC lifelong given high mixed AF/AFL coexistence — ACC/AHA 2024 (PMID 38753446)inputs: hr, creatinine_egfradvance: Acute strategy + AC + EP referral booked for 3D mapping
- 9DISPOSITIONAdmit if unstable, new HF, AAD initiation (esp dofetilide REMS), recent ablation, or peri-ablation bridging; discharge if rate-controlled with AC and EP referraladvance: Disposition documented
- 10MONITORINGTelemetry; QTc on dofetilide / sotalol / amiodarone; post-ablation observation for groin hematoma, tamponade, atrioesophageal fistula (LA ablation higher risk than CTI); AC adherenceinputs: ecg_12_leadadvance: Monitoring orders documented
- 11FOLLOWUPEP for 3D mapping ablation; cardiology q3–6 mo; AC continuation per CHA2DS2-VASc (lifelong given mixed AF/AFL); lifestyle (alcohol, weight, OSA); post-ablation 4-week ECG + Holter at 3/6/12 mo for AF screenadvance: Follow-up booked + ablation pathway entered