This handout is for typical (cti-dependent) atrial flutter. Your care team identified this based on: sawtooth flutter waves negative in ii/iii/avf (counterclockwise cti-dependent reentry).
Other reasons your team may use this plan: palpitations with regular narrow-complex tachy at hr ~150 (2:1 av conduction signature); recurrent typical flutter after prior cardioversion → cti ablation candidate.
Take these medications exactly as prescribed. Do not stop or change a dose without talking to your provider.
| Medication | Starting dose | How | When | What it does |
|---|---|---|---|---|
| metoprolol_tartrate | 5 mg IV q5min × 3 then 25–50 mg PO BID | IV/PO | IV q5min × 3 → PO BID | AVN slowing for 2:1 conducted typical flutter; HR target 80–110 — ACC/AHA 2024 (PMID 38753446) |
| metoprolol_succinate | 25–50 mg PO daily | PO | once daily | Long-acting BB bridge to CTI ablation — ACC/AHA 2024 |
| diltiazem | 0.25 mg/kg IV bolus → 5–15 mg/h infusion; 120–360 mg PO daily | IV/PO | IV bolus + infusion → PO daily | AVN slowing alternative; AVOID in HFrEF EF<40 — ACC/AHA 2024 (PMID 38753446) |
| ibutilide | 1 mg IV over 10 min (0.01 mg/kg if <60 kg); may repeat ×1 | IV | single dose, may repeat once | Ibutilide ~60% conversion rate for typical flutter (vs ~30% for AF); monitor QT 4 h post-dose for torsades (~3% risk) — ACC/AHA 2024 (PMID 38753446) |
| apixaban | 5 mg BID (2.5 mg BID if 2 of: ≥80 yr, ≤60 kg, Cr ≥1.5) | PO | BID | AC same as AF; mandatory 4-week post-CV AC regardless of score — ACC/AHA 2024 Class I (PMID 38753446); ARISTOTLE (PMID 21870978) |
| rivaroxaban | 20 mg with food (15 mg if CrCl 15–50) | PO | once daily | X-VeRT (PMID 24837375) — peri-CV efficacy = warfarin; ROCKET-AF foundational |
Plan: Typical CTI-dependent atrial flutter — rate control + AC + curative CTI ablation pathway — ACC/AHA 2024 (Joglar PMID 38753446); Calkins HRS/EHRA/ECAS 2007 (PMID 17572388)
Contact your care team if any of the following happen:
Call 911 or go to the nearest emergency room right away if you have:
EP for CTI ablation within 4–8 weeks (Class I); cardiology q3–6 mo; AC continuation per CHA2DS2-VASc; lifestyle (alcohol, weight, OSA); post-ablation 4-week ECG + Holter at 3 mo
Guideline: 2024 ACC/AHA/ACCP/HRS AF + AFL Joint Guideline (Joglar Circulation 2024 PMID 38753446); ESC 2024 AF (Van Gelder EHJ 2024 PMID 39050851); HRS/EHRA/ECAS 2007 catheter ablation expert consensus (Calkins PMID 17572388)