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Patient handout

Brugada syndrome (chronic ambulatory — SCD risk stratification)

PRODUCTION

1. Your condition

This handout is for brugada syndrome (chronic ambulatory — scd risk stratification). Your care team identified this based on: type 1 brugada ecg (coved st ≥2 mm v1–v2), spontaneous or provoked.

Other reasons your team may use this plan: unexplained syncope (often nocturnal / at rest); aborted scd / family history of scd or brugada; arrhythmia/syncope during febrile illness.

2. Your medications

Take these medications exactly as prescribed. Do not stop or change a dose without talking to your provider.

MedicationStarting doseHowWhenWhat it does
acetaminophen650–1000 mgPOq6h PRN feverAggressive prompt antipyresis — fever unmasks/triggers Brugada VF; patient-held fever action plan (2022 ESC VA)
avoid brugadadrugs.org agents (class IC/IA Na-blockers, select psychotropics, cocaine, excess alcohol)Na-channel-blocking and other listed drugs precipitate type 1 pattern + VF — lifelong avoidance (brugadadrugs.org; 2013 consensus)

Plan: Brugada syndrome SCD-protection (2013 HRS/EHRA/APHRS; 2017 AHA/ACC/HRS VA; 2022 ESC VA)

3. When to call your provider

Contact your care team if any of the following happen:

  • VF / electrical storm → ED + acute Brugada-storm pathway — 2022 ESC VA
  • New arrhythmic syncope → re-stratify, expedite ICD — 2017 AHA/ACC/HRS VA
  • Recurrent ICD shocks → quinidine then ablation — 2022 ESC VA

4. When to seek emergency care

Call 911 or go to the nearest emergency room right away if you have:

  • Aborted SCD / documented sustained VT/VF — secondary-prevention ICD Class I — 2017 AHA/ACC/HRS VA(life-threatening)
  • Spontaneous type 1 ECG + arrhythmic (non-vasovagal) syncope — high risk; primary-prevention ICD — 2022 ESC VA
  • Febrile illness in BrS — fever unmasks type 1 + precipitates VF; aggressive antipyresis + low threshold for monitored setting (esp. pediatric) — 2022 ESC VA
  • Recurrent VF / ICD electrical storm — quinidine; refractory → epicardial RVOT substrate ablation — 2022 ESC VA(life-threatening)
  • Patient on a brugadadrugs.org agent (class IC/IA Na-blocker, select psychotropics, cocaine) — deprescribe/substitute; class IC contraindicated for AF in BrS — brugadadrugs.org
  • Pregnancy with BrS — ICD compatible, aggressive fever management, avoid brugadadrugs.org agents incl. some tocolytics/anesthetics; cardio-obstetric — ESC 2018 Pregnancy

5. Follow-up

First-degree family cascade screening; lifelong drug-avoidance + fever education

6. Sources

Guideline: 2013 HRS/EHRA/APHRS Inherited Arrhythmia Expert Consensus + 2017 AHA/ACC/HRS VA Guideline + 2022 ESC Ventricular Arrhythmia Guideline

  1. pubmed.ncbi.nlm.nih.gov/23994779
  2. pubmed.ncbi.nlm.nih.gov/29084731
  3. pubmed.ncbi.nlm.nih.gov/36017572