Cardiogenic shock — Post-CABG
Phase E variant of cardio.cardiogenic-shock.core.v1 — narrowed to post-CABG cardiogenic shock (low CO state hours-to-days after cardiac surgery). Differential: vasoplegic syndrome (~10%), perioperative MI (graft failure), acute valvular dysfunction (esp. combined CABG+valve), tamponade (loculated post-pericardiotomy hemopericardium), pump failure (myocardial stunning, baseline LV dysfunction unmasked). Workup centerpiece: STAT TEE for tamponade + valve + LV/RV function. Treatment: NE first-line per SOAP-II; vasopressin add-on for vasoplegia (esp pre-op ACE-I); methylene blue 1-2 mg/kg IV for refractory vasoplegia (CONTRAINDICATED in G6PD deficiency + SSRIs); IABP via femoral cannulation; Impella; VA-ECMO if biventricular; EMERGENT RE-EXPLORATION if hemorrhagic tamponade. Manifest pointer reuses cardio.cardiogenic-shock.core.v1 manifest. Design-brief pointer reuses parent (post-CABG-specific differences documented inline). Status INTEGRATED until terminology + RxNav-validated drug codes are reconciled. Authored 2026-05-14 by shard-06-cardio-acute as Phase E wave 7 variant.
Entry points (4)
- historyHours-to-days post-CABG/valve surgery: SBP <90 + lactate ↑ + low CI on PA cathpost_cardiac_surgery_low_co
- imagingPost-op TEE: pericardial collection with chamber compression OR new severe valvular dysfunctiontee_post_op_tamponade_or_valve
- symptomRising chest tube output >200 mL/h × 4h or sudden cessation of drainage with hemodynamic deterioration (loculated tamponade)rising_chest_tube_output
- lab_abnormalityRising lactate post-cardiotomy with low SvO2 → low CO syndromerising_lactate_post_cardiotomy
Required inputs (9)
- sbprequiredvital • used at RED_FLAGSSBP <90 sustained drives shock-trigger threshold; vasoplegia presents with widely distributive picture (low SVR)
- cvprequiredvital • used at INITIAL_WORKUPCVP differentiates tamponade (high CVP + equalization) vs vasoplegia (low to normal CVP)
- tee_post_oprequiredimaging • used at INITIAL_WORKUPSTAT TEE for tamponade (loculated post-pericardiotomy effusion), valve dysfunction (paravalvular leak after combined CABG+valve), and global LV/RV function
- ecgrequiredimaging • used at INITIAL_WORKUPNew ST elevation in graft territory → graft failure (kink, embolization, anastomotic problem)
- lactaterequiredlab • used at RED_FLAGSLactate trend marks SCAI Stage C+; rising lactate after off-bypass is hallmark of low CO syndrome
- svo2_or_scvo2requiredlab • used at INITIAL_WORKUPMixed or central venous oxygen saturation marker of CO adequacy; low SvO2 + low MAP confirms low CO state
- troponinrequiredlab • used at INITIAL_WORKUPPerioperative MI threshold per 4th UDMI: troponin >10x ULN + ECG/imaging changes; helps identify graft failure
- creatininerequiredlab • used at CONTEXTAKI common post-CPB; eGFR for drug dosing
- chest_tube_outputrequiredhistory • used at CONTEXTChest tube output trend: rising = active bleeding; sudden drop + hemodynamic decline = loculated tamponade
12-phase flow (11)
- 1FRAMEPost-CABG CS = differential of vasoplegia vs tamponade vs perioperative MI vs valvular dysfunction vs pump failure; cardiac surgery and CT anesthesia must be at bedside; STAT TEE is criticalinputs: sbp, lactateadvance: CT surgery + anesthesia + TEE team activated
- 2ENTRYIdentify primary etiology: tamponade (re-explore), vasoplegia (vasopressors + methylene blue), graft failure (re-cath), valve dysfunction (re-operate), pump failure (inotropes + MCS)inputs: sbp, cvpadvance: Etiology hypothesis from TEE + ECG + chest tube output
- 3CONTEXTPre-op LV function, type of surgery (on-pump vs off-pump, combined CABG + valve), CPB time, cross-clamp time, intraoperative events, anticoagulation statusinputs: chest_tube_output, creatinineadvance: OR record reviewed
- 4RED_FLAGSHemorrhagic tamponade (rising chest tube output suddenly stopping + hypotension) → emergent re-exploration; massive transfusion + activate trauma protocolinputs: sbp, cvpactions: cardiac_tamponadeadvance: Re-exploration decision made
- 5INITIAL_WORKUPSTAT TEE (tamponade, valve, LV/RV function); ECG (graft territory ischemia); ABG + lactate + SvO2; chest tube output trend; CXR for hemothoraxinputs: tee_post_op, ecg, lactate, svo2_or_scvo2, troponinactions: cardiogenic_shock, panel.cardiac, panel.coagadvance: Etiology classified
- 6BRANCHING_WORKUPTamponade → emergent re-exploration; graft failure with persistent ischemia → re-cath; vasoplegia → escalate pressors + methylene blue; pump failure → inotropes + MCSinputs: tee_post_opactions: acs_pathwayadvance: Etiology-specific intervention triggered
- 7RISK_STRATIFICATIONSCAI 2022 staging; STS predicted operative risk vs observed outcome; CardShock for perioperative CSinputs: lactateadvance: Risk stratified
- 8TREATMENTNorepinephrine first-line per SOAP-II; vasopressin add-on for vasoplegia (esp if pre-op ACE-I); methylene blue 1-2 mg/kg IV for refractory vasoplegia; epinephrine + dobutamine if low CI; IABP femoral if persistent low CO; Impella for LV failure; VA-ECMO if biventricular; EMERGENT RE-EXPLORATION if hemorrhagic tamponadeinputs: sbp, lactateactions: cardiogenic_shockadvance: Pressor + inotrope + MCS strategy active and source addressed
- 9DISPOSITIONCT-ICU; advanced HF center transfer if persistent shock + LVEF <30 + non-recoverableadvance: Disposition assigned
- 10MONITORINGA-line + central line + PA catheter (typically already in place from OR); chest tube output q1h; lactate + ABG q2h; daily TEE for valve + LV/RV recovery; methylene blue serotonin syndrome screen if on SSRIinputs: lactateactions: panel.cardiacadvance: Monitoring cadence established
- 11FOLLOWUPGDMT initiation if persistent LV dysfunction (PIONEER-HF cadence); cardiac rehab post-CABG; sternal precautions; depression screening (high prevalence)advance: GDMT + cardiac rehab + follow-up booked