This handout is for post-cardiac-arrest care — drowning-induced cardiac arrest. Your care team identified this based on: rosc after submersion / drowning-induced cardiac arrest (aha 2020 §drowning).
Other reasons your team may use this plan: comatose patient post-drowning with core temp <32 °c — extended acls warranted; ttm candidate (schneider 2014 pmid 25034567); witnessed drowning + low-flow <90 min + core temp 28-32 °c with vf/asystole — ecmo/ecpr consideration (elso drowning protocol).
Take these medications exactly as prescribed. Do not stop or change a dose without talking to your provider.
| Medication | Starting dose | How | When | What it does |
|---|---|---|---|---|
| norepinephrine | 0.05-0.5 µg/kg/min titrate MAP ≥65 | IV | continuous | SOAP-II PMID 20200382; first-line post-ROSC vasoactive |
| amiodarone | 300 mg IV bolus → 150 mg if recurrent → 1 mg/min × 6h → 0.5 mg/min × 18h; HOLD additional doses if core <30 °C | IV | modified for hypothermia | AHA 2020 ACLS Class IIb; in hypothermia limit to 1 dose until warmed >30 °C, then resume standard cadence |
| epinephrine | 1 mg IV q3-5 min if normothermic; if core <30 °C → withhold further doses; if 30-34 °C → space q6-10 min | IV | modified for hypothermia | AHA 2020 ACLS — modified dosing intervals for hypothermia |
| magnesium sulfate | 1-2 g IV | IV | one-time + repeat for TdP | AHA 2020 ACLS Class IIa for TdP; correct hypomagnesemia first |
| propofol | 5-50 µg/kg/min | IV | continuous; titrate RASS | PADIS 2018; hepatic metabolism slowed in hypothermia → reduce dose during cooling |
| fentanyl | 25-200 µg/h | IV | continuous | PADIS 2018; analgesia + shivering suppression for TTM |
| tranexamic acid | 1 g IV over 10 min | IV | within 3h of bleeding onset | CRASH-2 PMID 20554319 if traumatic bleeding co-existing with drowning |
| ceftriaxone | 2 g IV daily | IV | daily | Early empiric for aspiration pneumonia from drowning — typically broad gram-negative + anaerobe coverage; consider piperacillin-tazobactam if water-source contamination concern |
Plan: Drowning-induced post-arrest phenotype — modified ACLS for hypothermia + active warming + ARDS management + ECPR bridge consideration (AHA 2020 + Schneider 2014 + ELSO drowning)
Contact your care team if any of the following happen:
Call 911 or go to the nearest emergency room right away if you have:
Pulmonology follow-up for ARDS sequelae; cardiology + EP follow-up if cardiac trigger (LQTS, Brugada, structural); rehab for cognitive sequelae; mental health (post-arrest PTSD, family); substance-use referral if alcohol/drug precipitated; aquatic safety education
Guideline: AHA 2020 ACLS / Post-Cardiac-Arrest Care drowning + hypothermia sections + ELSO drowning consensus + ARDSnet + PROSEVA + Schneider 2014 cold-water drowning