This handout is for transient ischemic attack (tia). Your care team identified this based on: transient focal neurologic deficit (resolved or resolving) per aha/asa 2021.
Other reasons your team may use this plan: transient monocular blindness (amaurosis fugax) per aha/asa 2021; transient aphasia / expressive or receptive (aha/asa 2021); transient hemiparesis or hemisensory loss (aha/asa 2021).
Take these medications exactly as prescribed. Do not stop or change a dose without talking to your provider.
| Medication | Starting dose | How | When | What it does |
|---|---|---|---|---|
| aspirin | 325 mg load → 81 mg | PO | load once → 81 mg daily maintenance | Foundational antiplatelet per AHA/ASA 2021; load 325 mg if not already on aspirin; 81 mg lifelong |
| clopidogrel | 600 mg load → 75 mg | PO | load once → 75 mg daily × 21 d | CHANCE / POINT — DAPT × 21 d (POINT: 21 d optimal, after which bleeding risk exceeds benefit) then aspirin alone |
| ticagrelor | 180 mg load → 90 mg BID | PO | BID × 30 d | THALES Johnston NEJM 2020 — ticagrelor + aspirin × 30 d non-inferior; useful if CYP2C19 LOF (e.g., East Asian) |
Plan: Acute antithrombotic for TIA (within 24 h of symptom onset)
Use these zones to know what to do based on how you feel.
Call 911 or go to the nearest emergency room right away if you have:
Neurology / vascular clinic at 1–2 wks per AHA/ASA 2021; PCP at 1–4 wks; cardiac rehab if appropriate; vaccinations; depression screen
Guideline: 2021 AHA/ASA Stroke Prevention Guidelines (after stroke / TIA) + 2024 AHA Primary Prevention of Stroke