Lower GI Bleeding
Manifest is full and current (ACG 2023 + ESGE 2021 + BSG 2019 + Villanueva 2013 + Green 2005 + Strate 2003) with 10 phenotypes (diverticular, hemorrhoidal, CRC, angiodysplasia, IBD, ischemic, post-polypectomy, radiation proctitis, massive, on-anticoag) and full medication/dosing tables. Problem-package at assessment-of-lower-gastrointestinal-bleeding/ with full atom set; design brief lives at sibling gi.gi_bleed.acute/_design-brief.md (shared with UGIB). Workup `lgib` is registered in clinical-tools-registry. Oakland score is referenced as manual interpretation rule (calc_oakland not yet in BUILTIN_CALCULATORS — calc.has_bled, calc.map, calc.news2 wired instead). Gaps for PRODUCTION: evidence.pmids array empty (manifest cites guideline labels but no numeric PMIDs); no engine-specific test_files; no regimen_axes (PRBC, IV crystalloid, PPI empiric, vitamin K, 4-factor PCC, idarucizumab, andexanet alfa wired in manifest.medications without RxCUI verification). Calculator gap: Oakland score not yet implemented as a BUILTIN_CALCULATOR — add for full INTEGRATED→PRODUCTION promotion.
Entry points (4)
- symptomHematochezia (bright red blood per rectum) (ACG 2024)hematochezia
- symptomMelena (consider brisk upper source — ~15% of apparent LGIB) (ACG 2024)melena_with_lower_source
- symptomSyncope / presyncope with rectal bleeding (ACG 2024)syncope_with_blood_loss
- lab_abnormalityAcute drop in hemoglobin (ACG 2024)acute_drop_in_hgb
Required inputs (16)
- agerequireddemographic • used at CONTEXTOakland score component; CRC risk if ≥45; angiodysplasia risk if elderly (ACG 2024)
- sbprequiredvital • used at CONTEXTHemodynamic instability defines massive LGIB; shock index (ACG 2024)
- hrrequiredvital • used at CONTEXTTachycardia / shock index >1 → unstable (ACG 2024)
- hemoglobinrequiredlab • used at INITIAL_WORKUPOakland score component; transfusion threshold (Hgb 7 per ACG 2023)
- plateletsrequiredlab • used at INITIAL_WORKUPCoagulopathy / thrombocytopenia management (ACG 2024)
- inrrequiredlab • used at INITIAL_WORKUPCoagulopathy reversal threshold; on-anticoagulation pathway (ACG 2024)
- creatininerequiredlab • used at INITIAL_WORKUPRenal function; contrast for CTA; medication dosing (ACG 2024)
- bun_creatinine_ratiorequiredlab • used at INITIAL_WORKUPElevated BUN:Cr ratio → upper source likelihood (ACG 2024)
- lactatelab • used at RED_FLAGSPerfusion marker in massive bleed (ACG 2024)
- cta_abdomen_pelvisimaging • used at BRANCHING_WORKUPFirst-line for hemodynamically significant LGIB per ACG 2023
- colonoscopyrequiredimaging • used at INITIAL_WORKUPDiagnostic + therapeutic for LGIB after bowel prep (ACG 2024)
- egd_exclude_upper_sourceimaging • used at BRANCHING_WORKUPExclude brisk upper source (~15% of apparent LGIB) (ACG 2024)
- anticoag_antiplateletrequiredhistory • used at CONTEXTHold/reverse decision; resume timing (ACG 2024)
- nsaid_userequiredhistory • used at CONTEXTDiscontinue NSAIDs after diverticular bleed (ACG 2023)
- recent_polypectomyhistory • used at CONTEXTPost-polypectomy bleed pathway (up to 14d post-procedure) (ACG 2024)
- known_diverticulosis_hemorrhoids_ibdhistory • used at CONTEXTPhenotype — diverticular / hemorrhoidal / IBD / radiation (ACG 2024)
12-phase flow (12)
- 1FRAMEConfirm LGIB scope; remember ~15% of apparent LGIB is brisk UGIB — keep EGD on the table (ACG 2024)inputs: ageadvance: lower source plausible
- 2ENTRYRecognize hematochezia, syncope with blood loss, or acute Hgb drop (ACG 2024)advance: one entry trigger present
- 3CONTEXTVitals, anticoag/antiplatelet/NSAID review, recent polypectomy, IBD history, prior GI bleeds, family CRC (ACG 2024)inputs: sbp, hr, anticoag_antiplatelet, nsaid_use, recent_polypectomy, known_diverticulosis_hemorrhoids_ibdadvance: context captured
- 4RED_FLAGSHemodynamic instability, massive hematochezia, syncope, ongoing active bleed, supratherapeutic anticoagulation, suspected upper source, peritoneal signs, Hgb <7, severe coagulopathy (ACG 2024)inputs: sbp, hr, hemoglobin, lactateadvance: unstable patient routed or stabilized
- 5INITIAL_WORKUPCBC, type and crossmatch, BMP, INR/aPTT, BUN:Cr ratio, lactate if severe; bowel prep; colonoscopy (ACG 2024)inputs: hemoglobin, platelets, inr, creatinine, bun_creatinine_ratio, colonoscopyactions: panel.cbc, panel.renal, lgibadvance: baseline labs + endoscopy plan
- 6BRANCHING_WORKUPCTA first if hemodynamically unstable (ACG 2023); EGD to exclude upper source; tagged RBC scan / capsule endoscopy if obscureinputs: cta_abdomen_pelvis, egd_exclude_upper_sourceadvance: phenotype identified (diverticular / hemorrhoidal / CRC / angiodysplasia / IBD / ischemic / post-polypectomy / radiation / massive / on-anticoag)
- 7DIFFERENTIALDiverticular > hemorrhoidal > CRC > angiodysplasia > IBD > ischemic > post-polypectomy > radiation > brisk UGIB > anal fissure (ACG 2024)advance: etiology identified
- 8RISK_STRATIFICATIONOakland score (≤8 → safe outpatient discharge per ACG 2023); shock index; NEWS2; HAS-BLED for anticoaginputs: hemoglobin, sbp, hractions: calc.has_bled, calc.news2, calc.mapadvance: risk score documented
- 9TREATMENTIV crystalloid, restrictive transfusion (Hgb 7; 8-9 if CAD/ACS), endoscopic hemostasis (clip/cautery/injection), CTA-guided embolization for massive, hold NSAIDs, continue aspirin for secondary CV prevention, discontinue NSAID after diverticular bleed (ACG 2024)inputs: hemoglobin, inradvance: hemostasis achieved or escalated
- 10DISPOSITIONICU for hemodynamic instability / massive transfusion; floor for stable LGIB; safe discharge if Oakland ≤ 8 (ACG 2024)inputs: sbp, hemoglobinadvance: destination set
- 11MONITORINGSerial Hgb q6-8h, vitals, stool output color/frequency, UOP, INR after reversal, rebleed surveillance 48-72h, lactate clearance if shock (ACG 2024)inputs: hemoglobinadvance: stable for 24h or escalated
- 12FOLLOWUPDischarge if Oakland ≤8; outpatient colonoscopy within 7d if not done; GI follow-up 2-4 weeks; anticoag resumption with cardiology; iron repletion; recurrence counseling (ACG 2024)advance: follow-up scheduled and counseled