This handout is for malaria (uncomplicated + severe). Your care team identified this based on: fever in returned traveler from endemic region (idsa 2024).
Other reasons your team may use this plan: cyclical fever, chills, diaphoresis (idsa 2024); jaundice, anemia, splenomegaly with fever (idsa 2024); resident of malaria-endemic region with fever (idsa 2024).
Take these medications exactly as prescribed. Do not stop or change a dose without talking to your provider.
| Medication | Starting dose | How | When | What it does |
|---|---|---|---|---|
| artesunate_iv | 2.4 mg/kg IV at 0, 12, 24 h then daily | IV | 0/12/24 h then daily until tolerating PO | SEAQUAMAT / AQUAMAT — superior to quinine (IDSA 2024) |
| artemether_lumefantrine | 4 tablets BID × 3 d (≥35 kg) | PO | BID × 3 d | Most widely used ACT (IDSA 2024) |
| quinine | 20 mg/kg IV load + 10 mg/kg q8h | IV | load + q8h | Backup; cinchonism, hypoglycemia (IDSA 2024) |
| clindamycin | 20 mg/kg/d divided | IV/PO | TID | Pregnancy 1st trimester regimen with quinine (IDSA 2024) |
Plan: Severe malaria — IV artesunate then ACT (IDSA 2024)
Contact your care team if any of the following happen:
Call 911 or go to the nearest emergency room right away if you have:
ID clinic, chemoprophylaxis counselling, relapse counselling vivax/ovale (IDSA 2024)
Guideline: WHO 2023 Guidelines for the Treatment of Malaria; CDC Yellow Book 2024