This handout is for uterine rupture (complete / incomplete dehiscence). Your care team identified this based on: sudden fetal bradycardia or prolonged deceleration (category iii fhr) in a patient undergoing tolac — most sensitive marker of uterine rupture (~ 70% of cases; ridgeway ajog 2004 pmid 14990414).
Other reasons your team may use this plan: severe, acute abdominal pain breaking through epidural analgesia in tolac — red flag for uterine rupture (acog pb 205 2019); loss of presenting part / change in fetal station on cervical exam during tolac — pathognomonic when present (low sensitivity) (acog pb 205 2019); maternal tachycardia + hypotension + signs of hemorrhagic shock during or after tolac — may reflect concealed intraperitoneal hemorrhage (acog pb 205 2019).
Take these medications exactly as prescribed. Do not stop or change a dose without talking to your provider.
| Medication | Starting dose | How | When | What it does |
|---|---|---|---|---|
| oxytocin | 10-40 IU in 1 L LR or NS post-delivery | IV infusion (peripheral large-bore) | continuous post-delivery | Atony prevention post-delivery (rupture is major hemorrhage source; ACOG PB 183 2017 uterotonic ladder applies) |
| tranexamic acid | 1 g IV over 10 min within 3 h of birth | IV | single dose; may repeat × 1 after 30 min if continued bleeding | WOMAN trial 2017 — TXA within 3 h reduces mortality from postpartum hemorrhage (PMID 28456509) |
Plan: Acute uterine rupture — resuscitation + emergent cesarean + DIC + repair-vs-hysterectomy + RhoGAM (ACOG PB 205 2019 + Pacheco SMFM 47 2019)
Contact your care team if any of the following happen:
Call 911 or go to the nearest emergency room right away if you have:
6-wk postpartum visit + rupture-specific anticipatory guidance: recurrence 6-32% in subsequent pregnancy (ACOG PB 205 2019); preconception MFM mandatory; elective cesarean at 36-37 wk for next pregnancy; NO TOLAC in subsequent pregnancy; close 3rd-trimester surveillance for warning signs; thrombophilia / PAS workup if recurrent; addiction medicine if substance use; IPV referral if trauma-related; smoking cessation; HTN surveillance if HTN-driven; mental health screen (EPDS + PCL-5 for peripartum-PTSD given catastrophic event); contraception counseling; immunization audit; newborn outpatient 24-48 h post-discharge peds visit + HIE-cooling follow-up + developmental tracking for first year if hypoxic exposure.
Guideline: ACOG Practice Bulletin 205 (2019, reaffirmed 2024) — Vaginal Birth After Cesarean Delivery (VBAC) — covers uterine rupture in TOLAC context + ACOG / SMFM joint consensus on TOLAC + Landon MB et al — Maternal and perinatal outcomes associated with a trial of labor after prior cesarean delivery (MFMU Network, N Engl J Med 2004; 351(25): 2581-2589; PMID 15598960) + Ridgeway JJ et al — Fetal heart rate changes associated with uterine rupture (Am J Obstet Gynecol 2004; 103(3): 506-512; PMID 14990414) + Pacheco LD et al — An update on the use of massive transfusion protocols in obstetrics (Am J Obstet Gynecol 2016; 214(3): 340-344; PMID 26348379) + Silver RM et al — Center of Excellence for Placenta Accreta (Am J Obstet Gynecol 2015; 212(5): 561-568; PMID 25460838) + ACOG PB 181 2017 Anti-D Immunoprophylaxis + ACOG PB 183 2017 Postpartum Hemorrhage + WOMAN trial Shakur 2017 (PMID 28456509) — TXA in PPH (carryover to rupture-delivery PPH)