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Patient handout

Acute conjunctivitis (viral / bacterial / allergic, with red-flag red-eye routing)

PRODUCTION

1. Your condition

This handout is for acute conjunctivitis (viral / bacterial / allergic, with red-flag red-eye routing). Your care team identified this based on: acute red eye with discharge or crusting/glued lids — the conjunctivitis presentation; subtype not yet assigned (azari jama 2013; aao conjunctivitis ppp, varu 2018).

Other reasons your team may use this plan: bilateral itchy, watery, chemotic eyes ± seasonality / atopy — allergic conjunctivitis entry (azari jama 2013 — itch is the most consistent allergic sign); unilateral (then fellow-eye) watery red eye, follicular reaction, tender preauricular node — adenoviral / ekc entry, infection-control flag (liu cochrane 2022; aao ppp varu 2018); hyperacute copious purulent discharge over hours with marked lid edema — gonococcal conjunctivitis (ophthalmic emergency, corneal-perforation risk) (cdc sti 2021; azari jama 2013).

2. Your medications

Take these medications exactly as prescribed. Do not stop or change a dose without talking to your provider.

MedicationStarting doseHowWhenWhat it does
sight_threat_screen_route_out_if_positiveAAO Conjunctivitis PPP (Varu 2018) — these features mean it is NOT simple conjunctivitis; route OUT to ophtho.acute-red-eye / keratitis / anterior-uveitis / acute-angle-closure-glaucoma by engine_id before treating as conjunctivitis. Contact-lens red eye: discontinue lens, NEVER patch.

Plan: Acute conjunctivitis — subtype-stratified (stewardship-first; emergencies systemic + ophthalmology)

3. When to call your provider

Contact your care team if any of the following happen:

  • Any sight-threatening red flag → same-day ophthalmology, route to ophtho.acute-red-eye.core.v1 / keratitis / uveitis / angle-closure (AAO PPP Varu 2018)
  • Hyperacute purulent (gonococcal) / contact-lens keratitis suspicion / neonatal ophthalmia / herpetic → emergency ophthalmology + systemic Rx (CDC STI 2021)
  • Adenoviral/EKC outbreak in an institution → infection-control notification (Hamada 2008)

4. When to seek emergency care

Call 911 or go to the nearest emergency room right away if you have:

  • Hyperacute copious purulent discharge over hours, marked lid edema, rapid progression ± Gram-negative intracellular diplococci — gonococcal conjunctivitis (CDC STI 2021; Azari JAMA 2013)(life-threatening)
  • Contact-lens wearer with red eye + pain/photophobia/corneal infiltrate or fluorescein staining — microbial (Pseudomonas/Acanthamoeba) keratitis until excluded (Seal 1999; Truong 2018)
  • Significant deep pain, true photophobia, reduced visual acuity, ciliary/limbal flush, corneal opacity/infiltrate, fixed/irregular pupil — NOT simple conjunctivitis (AAO Conjunctivitis PPP, Varu 2018)
  • Neonate ≤28 days with conjunctivitis/discharge — ophthalmia neonatorum (gonococcal days 2-5, chlamydial days 5-14, chemical day 1) (CDC STI 2021)(life-threatening)
  • Unilateral red eye + corneal dendrite on fluorescein ± vesicular lid rash / decreased corneal sensation — HSV/VZV keratoconjunctivitis (AAO Conjunctivitis PPP, Varu 2018)

5. Follow-up

Stewardship + contagion + chronicity: counsel natural history and antibiotic-stewardship rationale (Everitt BMJ 2006 — immediate prescribing increases re-attendance and antibiotic belief); hygiene/return-to-activity guidance (adenoviral sheds ~10-14 d); ensure gonococcal/chlamydial partner treatment + STI follow-up + reporting; recurrent/chronic or treatment-refractory conjunctivitis → ophthalmology (chronic chlamydial, atopic/vernal keratoconjunctivitis, mucous membrane pemphigoid, or ocular surface malignancy mimic — AAO PPP Varu 2018); vernal/atopic → long-term ophthalmology (cyclosporine 0.1% per updated PPP).

6. Sources

Guideline: AAO Conjunctivitis Preferred Practice Pattern (Varu et al, Ophthalmology 2018; updated as Conjunctivitis PPP 2023, republished Ophthalmology 2024 — substance unchanged, confirmed current 2026-05-17) + Azari & Barney JAMA 2013 systematic review + Sheikh et al Cochrane 2012 (antibiotics vs placebo for acute bacterial conjunctivitis) + Rietveld et al BMJ 2004 (bacterial-cause clinical prediction rule) + Everitt et al BMJ 2006 (delayed-prescribing RCT) + CDC STI Treatment Guidelines 2021 (gonococcal/chlamydial/ophthalmia neonatorum) + Liu et al Cochrane 2022 (EKC topical therapy)

  1. pubmed.ncbi.nlm.nih.gov/30366797
  2. pubmed.ncbi.nlm.nih.gov/24150468
  3. pubmed.ncbi.nlm.nih.gov/22972049