Typical (CTI-dependent) atrial flutter
Encounter flow
11/12 authoredCanonical 12-phase frame with authored status for this dossier.
Frame
Confirm typical CTI-dependent flutter (sawtooth negative II/III/aVF, atrial ~300 bpm, ventricular often ~150 with 2:1) → curative ablation candidate per ACC/AHA 2024 Class I
Typical flutter morphology confirmed
Patient inputs (9)
CHA2DS2-VASc + ablation candidacy
HR ~150 = pathognomonic 2:1 AV conduction in typical flutter; rate target 80–110
Negative sawtooth in II/III/aVF + positive in V1 confirms CTI-dependent counterclockwise circuit (Saoudi 2001 PMID 11428013)
Thyrotoxic flutter — reversible cause; may not need ablation if TFTs normalize
DOAC dosing + contrast for ablation procedure
LA size, EF, valvular disease — ablation safety + LV dysfunction screen
SBP <90 with flutter RVR → emergent DCCV (lower energy than AF, 50–100 J biphasic)
AC indication identical to AF (Class I ACC/AHA 2024)
HAS-BLED + ablation peri-procedure bleed risk
* = hard-required. Engine cannot meaningfully run until these are filled.
Severity triggers (6)
- informationallife_threateningunstable_typical_flutter_requires_emergent_dccvTypical CTI flutter with SBP <90, AMS, ongoing ischemia, or pulmonary edema → synchronized DCCV 50–100 J biphasic nowTrigger could not be auto-evaluated — needs clinician judgement.
- informationallife_threateningpost_ablation_cardiac_tamponadeHypotension + new pericardial effusion within hours of CTI ablation → emergent pericardiocentesisTrigger could not be auto-evaluated — needs clinician judgement.
- informationallife_threateningpost_ablation_atrioesophageal_fistulaFever + chest pain + new neurologic deficit 2–6 weeks post-ablation (rare in CTI but reported) → emergency surgical evaluationTrigger could not be auto-evaluated — needs clinician judgement.
- informationalsevereac_related_bleed_during_4wk_windowGI bleed, intracranial bleed, or major bleed during mandatory 4-week post-CV AC windowTrigger could not be auto-evaluated — needs clinician judgement.
- informationalsevereav_node_ablation_consideration_for_uncontrolled_RVRPersistent uncontrolled RVR despite max AVN blockade + failed CTI ablation + symptomatic — consider AV node ablation + permanent pacemakerTrigger could not be auto-evaluated — needs clinician judgement.
- informationalmoderaterecurrent_typical_flutter_on_aad_pre_ablationRecurrent typical flutter despite metoprolol + amiodarone → expedite CTI ablationTrigger could not be auto-evaluated — needs clinician judgement.
Workflow calculators
Run this disease's risk and dosing calculators inline.
Recommended regimen
Typical CTI-dependent atrial flutter — rate control + AC + curative CTI ablation pathway — ACC/AHA 2024 (Joglar PMID 38753446); Calkins HRS/EHRA/ECAS 2007 (PMID 17572388)- metoprolol_tartratefirst linebeta_blocker5 mg IV q5min × 3 then 25–50 mg PO BID • IV/PO • IV q5min × 3 → PO BIDtriggers: typical_flutter_with_RVR, no_HFrEF_decompensationAVN slowing for 2:1 conducted typical flutter; HR target 80–110 — ACC/AHA 2024 (PMID 38753446)rxcui 203191
- metoprolol_succinatefirst linebeta_blocker25–50 mg PO daily • PO • once dailytriggers: chronic_rate_control_pre_ablationLong-acting BB bridge to CTI ablation — ACC/AHA 2024rxcui 866427
- diltiazemfirst linenon_DHP_CCB0.25 mg/kg IV bolus → 5–15 mg/h infusion; 120–360 mg PO daily • IV/PO • IV bolus + infusion → PO dailytriggers: BB_intolerant, EF_preserved, COPD_with_bronchospasmAVN slowing alternative; AVOID in HFrEF EF<40 — ACC/AHA 2024 (PMID 38753446)rxcui 3443
- ibutilidefirst lineclass_III_AAD1 mg IV over 10 min (0.01 mg/kg if <60 kg); may repeat ×1 • IV • single dose, may repeat oncetriggers: stable_typical_flutter_chemical_CV, baseline_QTc_<440Ibutilide ~60% conversion rate for typical flutter (vs ~30% for AF); monitor QT 4 h post-dose for torsades (~3% risk) — ACC/AHA 2024 (PMID 38753446)rxcui 41289
- apixabanfirst lineDOAC_factor_Xa5 mg BID (2.5 mg BID if 2 of: ≥80 yr, ≤60 kg, Cr ≥1.5) • PO • BIDtriggers: CHA2DS2VASc_>=2_men_>=3_women, pre_post_cardioversion, pre_post_CTI_ablationAC same as AF; mandatory 4-week post-CV AC regardless of score — ACC/AHA 2024 Class I (PMID 38753446); ARISTOTLE (PMID 21870978)rxcui 1364430
- rivaroxabanfirst lineDOAC_factor_Xa20 mg with food (15 mg if CrCl 15–50) • PO • once dailytriggers: CHA2DS2VASc_>=2, apixaban_unavailableX-VeRT (PMID 24837375) — peri-CV efficacy = warfarin; ROCKET-AF foundationalrxcui 1114195
outpatient playbook — drug actions (2)
- 1. continue DOAC if CHA2DS2-VASc ≥2rxcui 1364430apixaban 5 mg BID per CHA2DS2-VASc • PO • BIDtrigger: Persistent stroke riskLifelong AC — ACC/AHA 2024 Class I
- 2. discontinue rate-control AAD post-successful ablationrxcui 866427Wean metoprolol over 4–8 weeks if no recurrence • PO • tapertrigger: Successful CTI ablation + no recurrence at 3 moNo further AAD needed if CTI ablation successful — ACC/AHA 2024
Auto-drafted A&P note
outpatientSubjective
- Possible entry pathways: Sawtooth flutter waves negative in II/III/aVF (counterclockwise CTI-dependent reentry); Palpitations with regular narrow-complex tachy at HR ~150 (2:1 AV conduction signature); Recurrent typical flutter after prior cardioversion → CTI ablation candidate.
Objective
- No vitals, labs, or imaging entered for this encounter.
Assessment
**Typical (CTI-dependent) atrial flutter** (cardio.atrial_flutter.typical-cavotricuspid.v1). Scope: Confirm typical CTI-dependent flutter (sawtooth negative II/III/aVF, atrial ~300 bpm, ventricular often ~150 with 2:1) → curative ablation candidate per ACC/AHA 2024 Class I No severity triggers fired against current inputs.
Plan
Regimen axis: **Typical CTI-dependent atrial flutter — rate control + AC + curative CTI ablation pathway — ACC/AHA 2024 (Joglar PMID 38753446); Calkins HRS/EHRA/ECAS 2007 (PMID 17572388)**. 1. metoprolol_tartrate 5 mg IV q5min × 3 then 25–50 mg PO BID IV/PO IV q5min × 3 → PO BID (beta_blocker, first line) — AVN slowing for 2:1 conducted typical flutter; HR target 80–110 — ACC/AHA 2024 (PMID 38753446) 2. metoprolol_succinate 25–50 mg PO daily PO once daily (beta_blocker, first line) — Long-acting BB bridge to CTI ablation — ACC/AHA 2024 3. diltiazem 0.25 mg/kg IV bolus → 5–15 mg/h infusion; 120–360 mg PO daily IV/PO IV bolus + infusion → PO daily (non_DHP_CCB, first line) — AVN slowing alternative; AVOID in HFrEF EF<40 — ACC/AHA 2024 (PMID 38753446) 4. ibutilide 1 mg IV over 10 min (0.01 mg/kg if <60 kg); may repeat ×1 IV single dose, may repeat once (class_III_AAD, first line) — Ibutilide ~60% conversion rate for typical flutter (vs ~30% for AF); monitor QT 4 h post-dose for torsades (~3% risk) — ACC/AHA 2024 (PMID 38753446) 5. apixaban 5 mg BID (2.5 mg BID if 2 of: ≥80 yr, ≤60 kg, Cr ≥1.5) PO BID (DOAC_factor_Xa, first line) — AC same as AF; mandatory 4-week post-CV AC regardless of score — ACC/AHA 2024 Class I (PMID 38753446); ARISTOTLE (PMID 21870978) 6. rivaroxaban 20 mg with food (15 mg if CrCl 15–50) PO once daily (DOAC_factor_Xa, first line) — X-VeRT (PMID 24837375) — peri-CV efficacy = warfarin; ROCKET-AF foundational Setting playbook (outpatient) — Long-term post-CTI ablation surveillance, AC management based on CHA2DS2-VASc and ablation success, lifestyle modification, screening for incident AF (~25% post-CTI ablation) — ACC/AHA 2024 (PMID 38753446) 7. continue DOAC if CHA2DS2-VASc ≥2 apixaban 5 mg BID per CHA2DS2-VASc PO BID — Persistent stroke risk (Lifelong AC — ACC/AHA 2024 Class I) 8. discontinue rate-control AAD post-successful ablation Wean metoprolol over 4–8 weeks if no recurrence PO taper — Successful CTI ablation + no recurrence at 3 mo (No further AAD needed if CTI ablation successful — ACC/AHA 2024) Non-pharmacologic actions: - Lifestyle: weight, alcohol limit, OSA treatment, exercise (ACC/AHA 2024) - Vaccinations + secondary prevention bundle (ACC/AHA 2024) AVOID / contraindication checks: - Beta blocker block if decompensated HF — ACC/AHA 2024 (PMID 38753446) - Non DHP CCB block if EF lt 40 — ACC/AHA 2024 (PMID 38753446) - Ibutilide monitor QT 4h_post_dose — ACC/AHA 2024 (PMID 38753446) - Flutter CV requires AC 3wks or TEE — ACC/AHA 2024 (PMID 38753446) - DOAC renal dose adjustment — ESC 2024 (PMID 39050851)
Monitoring
Regimen monitoring: - telemetry continuous acute — ACC/AHA 2024 - HR target 80-110 pre ablation — ACC/AHA 2024 - QTc 4h post ibutilide — ACC/AHA 2024 - 4-week post-CV AC continuation regardless of CHA2DS2VASc — ACC/AHA 2024 Class I - post-ablation groin check first 4h then q4h ×24h — HRS 2007 (PMID 17572388) - post-ablation 4-week ECG + Holter 3mo for recurrence — Calkins 2007 Setting (outpatient) monitoring: - Cardiology q3–6 mo first year, then annually (ACC/AHA 2024) - Holter at 3, 6, 12 mo post-ablation (Calkins 2007) - CBC + eGFR q6m on DOAC (ESC 2024) Follow-up plan: EP for CTI ablation within 4–8 weeks (Class I); cardiology q3–6 mo; AC continuation per CHA2DS2-VASc; lifestyle (alcohol, weight, OSA); post-ablation 4-week ECG + Holter at 3 mo - Close-out criterion: Follow-up booked + ablation pathway entered Monitoring phase: Telemetry post-CV; QTc post-ibutilide × 4 h; post-ablation observation for groin hematoma + tamponade; AC adherence
Disposition
Current setting: outpatient — Long-term post-CTI ablation surveillance, AC management based on CHA2DS2-VASc and ablation success, lifestyle modification, screening for incident AF (~25% post-CTI ablation) — ACC/AHA 2024 (PMID 38753446) Disposition criteria: - Continue chronic surveillance; this engine continues unless transitions to AF predominant Escalation triggers (move to higher acuity): - Recurrent typical flutter despite ablation → repeat EP mapping — HRS 2007 - New AF after successful CTI ablation (~25%) → AF management via cardio.afib.core.v1 - Stroke / TIA on AC → workup + consider switch — ACC/AHA 2024
Earlier-Return Triggers
Return-precaution thresholds (watch for): - [LIFE_THREATENING] Typical CTI flutter with SBP <90, AMS, ongoing ischemia, or pulmonary edema → synchronized DCCV 50–100 J biphasic now - [LIFE_THREATENING] Hypotension + new pericardial effusion within hours of CTI ablation → emergent pericardiocentesis - [LIFE_THREATENING] Fever + chest pain + new neurologic deficit 2–6 weeks post-ablation (rare in CTI but reported) → emergency surgical evaluation
Citations
- 2024 ACC/AHA/ACCP/HRS AF + AFL Joint Guideline (Joglar Circulation 2024 PMID 38753446); ESC 2024 AF (Van Gelder EHJ 2024 PMID 39050851); HRS/EHRA/ECAS 2007 catheter ablation expert consensus (Calkins PMID 17572388) [PMID:38753446](https://pubmed.ncbi.nlm.nih.gov/38753446/) - Cited evidence (PMID 39050851) [PMID:39050851](https://pubmed.ncbi.nlm.nih.gov/39050851/) - Cited evidence (PMID 17572388) [PMID:17572388](https://pubmed.ncbi.nlm.nih.gov/17572388/) - Cited evidence (PMID 11428013) [PMID:11428013](https://pubmed.ncbi.nlm.nih.gov/11428013/) - Cited evidence (PMID 30874727) [PMID:30874727](https://pubmed.ncbi.nlm.nih.gov/30874727/) Last reconciled with current guidelines: 2026-05-14.
- 2024 ACC/AHA/ACCP/HRS AF + AFL Joint Guideline (Joglar Circulation 2024 PMID 38753446); ESC 2024 AF (Van Gelder EHJ 2024 PMID 39050851); HRS/EHRA/ECAS 2007 catheter ablation expert consensus (Calkins PMID 17572388) — PMID:38753446
- Cited evidence (PMID 39050851) — PMID:39050851
- Cited evidence (PMID 17572388) — PMID:17572388
- Cited evidence (PMID 11428013) — PMID:11428013
- Cited evidence (PMID 30874727) — PMID:30874727