Right-ventricular extension STEMI (proximal RCA)
Phase E variant of cardio.stemi.core.v1 — narrowed to right-ventricular extension of inferior STEMI (proximal RCA culprit). Inherits reperfusion + antiplatelet + statin regimen from parent via routing; specializes HEMODYNAMIC management — preload-dependent state requiring volume loading, dobutamine for refractory hypotension, and explicit Class III avoidance of nitrates/diuretics/morphine (AHA 2025). Manifest pointer reuses cardio.stemi.core.v1 manifest. Design-brief pointer reuses parent (RV-specific differences documented inline, anchored to Kinch & Ryan NEJM 1994 PMID 8208270). Status INTEGRATED until terminology + RxNav-validated drug codes are reconciled. Authored 2026-05-14 by shard-06-cardio-acute as part of Phase E variant batch (inferior/RV/posterior/LMCA).
Entry points (3)
- imagingV4R ST↑ ≥1 mm + inferior ST↑ II/III/aVF (RV-extension STEMI, proximal RCA)ecg_v4r_st_elevation_with_inferior
- symptomInferior STEMI + hypotension + clear lung fields + JVP elevation → presumptive RV extension; obtain V4R immediatelyinferior_stemi_with_hypotension_clear_lungs
- historyRouted from cardio.stemi.inferior.v1 after V4R+ confirmedinferior_stemi_referred_from_inferior_engine
Required inputs (9)
- agerequireddemographic • used at CONTEXTOlder patients with RV extension have higher mortality + decompensation risk
- sbprequiredvital • used at RED_FLAGSHypotension is the cardinal feature of RV-extension; preload-dependent state — fluid-responsive
- jvprequiredvital • used at RED_FLAGSElevated JVP + clear lungs + hypotension = classic RV infarct triad (Kinch & Ryan PMID 8208270)
- ecg_v4rrequiredimaging • used at INITIAL_WORKUPV4R ST↑ ≥1 mm = RV extension; obtained as Class I in all inferior STEMI per AHA 2025
- ecgrequiredimaging • used at INITIAL_WORKUPInferior ST↑ II/III/aVF; ST↑ III > II + V1 ST↑ supports proximal RCA culprit
- troponinrequiredlab • used at INITIAL_WORKUPConfirms infarct; RV troponin elevation typically modest given smaller mass than LV
- creatininerequiredlab • used at CONTEXTContrast nephropathy risk + dosing
- echo_post_pcirequiredimaging • used at MONITORINGRV size + function + TAPSE; confirm RV dilation/hypokinesis; assess for IVC plethora
- cor_angiorequiredimaging • used at TREATMENTProximal RCA culprit confirmation (lesion proximal to RV-marginal branches)
12-phase flow (10)
- 1FRAMERV-extension STEMI = proximal RCA culprit (lesion proximal to RV-marginal branches); ≈30-40% of inferior STEMIs have some RV involvement; preload-dependent hemodynamics dominate management — distinct from LV-dominant STEMI; route to cardio.stemi.core.v1 for the reperfusion arcinputs: ecg_v4radvance: V4R+ confirmed
- 2ENTRYCath lab within 90 min; bedside echo for RV size + function + TAPSE; IV access × 2 for fluid loadinginputs: age, sbpadvance: cath lab activated + IV access secured
- 3CONTEXTAllergies, bleed risk, recent surgery, antithrombotic regimen; medication reconciliation — STOP home nitrates, diuretics, morphine if recently administeredinputs: sbp, creatinine, jvpadvance: context complete; preload-reducer meds discontinued
- 4RED_FLAGSHypotension management (the dominant clinical problem); cardiogenic shock screen (RV-CS distinct from LV-CS); arrhythmias from atrial stretch (AF common with RV failure); concurrent inferior MI complications; preload optimization (NS 1-2L bolus, then dobutamine if persistent); STOP nitrates/diuretics/morphine (Class III AHA 2025)inputs: sbp, jvpactions: cardiogenic_shockadvance: hemodynamic strategy in place
- 5INITIAL_WORKUPECG + V4R + troponin + BMP + CBC + CXR + bedside echo (RV size, function, TAPSE, IVC, LV function, valvular)inputs: ecg, ecg_v4r, troponin, creatinine, echo_post_pciactions: acs_pathway, panel.cardiac, panel.renaladvance: workup documented
- 6BRANCHING_WORKUPPrimary PCI of proximal RCA; preserve RV-marginal branches if possible; complete revasc per COMPLETE if multivesselinputs: cor_angioadvance: reperfusion delivered
- 7TREATMENTStandard ACS regimen (ASA + ticagrelor + UFH + statin) per cardio.stemi.core.v1; CRITICAL: AVOID nitrates, diuretics, morphine (Class III AHA 2025 — preload reduction in preload-dependent state causes cardiovascular collapse); volume-load with NS 1-2L bolus then assess; dobutamine for persistent hypotension despite volume; defer BB until RV-failure resolvesinputs: sbp, jvp, creatinineactions: protocol.stemiadvance: reperfusion + hemodynamic strategy + bundle initiated
- 8DISPOSITIONCICU mandatory; RV failure can decompensate quicklyadvance: CICU bed assigned + hemodynamic plan documented
- 9MONITORINGCICU telemetry + arterial line if hypotension; serial echo for RV recovery (most RV function recovers within days-weeks of reperfusion); avoid preload reducers throughout admissioninputs: echo_post_pciactions: panel.cardiacadvance: RV recovering + BP stable off vasopressors
- 10FOLLOWUPCardiology follow-up; echo at 30 d for RV recovery confirmation; cardiac rehab (caution with diuretic prescription if persistent RV dysfunction)advance: cardiac rehab booked + RV function reassessed