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Patient handout

GERD (chronic, empiric-to-maintenance)

PRODUCTION

1. Your condition

This handout is for gerd (chronic, empiric-to-maintenance). Your care team identified this based on: heartburn / pyrosis.

Other reasons your team may use this plan: regurgitation / acid reflux; dysphagia (alarm symptom); chronic cough / laryngeal symptoms (extra-esophageal gerd).

2. Your medications

Take these medications exactly as prescribed. Do not stop or change a dose without talking to your provider.

MedicationStarting doseHowWhenWhat it does
omeprazole20 mg PO daily 30 min before breakfastPOdailyACG 2022 Katz — standard-dose PPI x 8 wk is first-line diagnostic-therapeutic maneuver
lansoprazole30 mg PO daily 30 min before breakfastPOdailyACG 2022 Katz — alternative standard-dose PPI
esomeprazole20 mg PO daily 30 min before breakfastPOdailyACG 2022 Katz — alternative PPI; S-isomer of omeprazole
pantoprazole40 mg PO daily 30 min before breakfastPOdailyACG 2022 Katz — alternative PPI; fewer CYP2C19 interactions
rabeprazole20 mg PO dailyPOdailyACG 2022 Katz — alternative PPI
dexlansoprazole30 mg PO dailyPOdailyACG 2022 Katz — dual-release PPI; may be taken without regard to meals

Plan: GERD empiric PPI step-up / step-down / maintenance — ACG 2022 Katz

3. Your action plan

Use these zones to know what to do based on how you feel.

GREENWell controlled — continue maintenance
If you have:
  • Heartburn <1x/week or none
  • No regurgitation
  • No dysphagia
  • Sleeping well, no nocturnal symptoms
Do this:
  • Continue current PPI at lowest effective dose (or on-demand if stepped down)
  • Maintain lifestyle modifications (weight, diet, meal timing, head-of-bed elevation)
  • Keep Barrett surveillance EGD appointments if applicable
  • Annual PPI step-down attempt with provider
YELLOWWorsening — contact provider within 1 week
If you have:
  • Heartburn >2x/week despite PPI
  • Regurgitation interfering with sleep or meals
  • Mild difficulty swallowing (occasional, solids only)
  • Need for daily antacids on top of PPI
Do this:
  • Verify PPI timing (30-60 min before breakfast)
  • Reinforce lifestyle: avoid late meals, elevate head of bed
  • Schedule appointment with provider to discuss step-up or EGD
Call your provider if:
  • Symptoms not improving after 2 weeks of adherence to PPI + lifestyle
  • New or worsening regurgitation
REDAlarm — seek urgent evaluation
If you have:
  • Difficulty swallowing solids or liquids (progressive dysphagia)
  • Painful swallowing (odynophagia)
  • Vomiting blood or coffee-ground material
  • Black tarry stools
  • Unintentional weight loss >5% in 3 months
  • Food impaction (cannot swallow saliva)
Do this:
  • Stop eating/drinking if food impaction — go to ED
  • Seek urgent/emergent evaluation for GI bleeding (ED)
  • Contact GI for urgent EGD referral
Call your provider if:
  • Any red zone symptom — do not wait

4. When to seek emergency care

Call 911 or go to the nearest emergency room right away if you have:

  • Dysphagia, odynophagia, GI bleeding, iron-deficiency anemia, unintentional weight loss, or recurrent vomiting in GERD patient (ACG 2022 Katz)
  • Barrett esophagus with high-grade dysplasia confirmed on expert pathology review (AGA 2024 Barrett)

5. Follow-up

Symptom reassessment at 8 wk; lifestyle reinforcement (weight loss, head-of-bed elevation, avoid late meals); long-term PPI safety counseling (bone, Mg, C. diff) (ACG 2022 Katz; NICE 2024)

6. Sources

Guideline: ACG 2022 Clinical Guideline: Diagnosis and Management of GERD (Katz Gastroenterology 2022)

  1. pubmed.ncbi.nlm.nih.gov/34807007
  2. pubmed.ncbi.nlm.nih.gov/29437910
  3. pubmed.ncbi.nlm.nih.gov/36228734